polymorphism | factor | odds ratio | pvalue | initial number | replication number | Population | age of cases | shorter lived allele | longer lived allele | study type | reference |
(HLA)-A1, B8, DR3 | — | — | 1.0 | 93 vs 100 | — | Irish | 80-97 years | — | — | Candidate Region/Gene | 12714268 |
rs4073591 | — | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
rs4930001 | — | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
rs16928120 | — | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
mtDNA C150T | — | — | 0.936 | 556 vs 403 | — | Chinese | 90–108 (94.59±3.34) | — | — | Candidate Region/Gene | 21262335 |
I carriers of ACE | — | — | 0.045 | 12 vs 190 vs 105 | — | Greek | 99-111 | — | — | Candidate Region/Gene | 23389097 |
3p24.2–22.3 | — | — | 0.037 | 632 (total) | — | Caucasian | By Expected age of death: Male 90-100, Female 95-104 | — | — | Genome-Wide Association Study | 20824210 |
9q31.3–34.2 | — | — | 0.054 | 632 (total) | — | Caucasian | By Expected age of death: Male 90-100, Female 95-104 | — | — | Genome-Wide Association Study | 20824210 |
XRCC3 intron 3 STR | — | — | 0.0005 | 430 (case) vs 290 | — | British | Mean age 70 | 15 | 13 | Candidate Region/Gene | 16518718 |
XRCC5 120 bp 5` (GAPyA)n STR | — | — | 0.0005 | 430 (case) vs 290 | — | British | Mean 70 | 16+2 | 15 | Candidate Region/Gene | 16518718 |
rs2338013 | — | 0.67 | 2.07e-06 | 763 vs 1085 | 754 vs 850 | German | Mean age 99.7 | — | — | Genome-Wide Association Study | 21740922 |
rs29228 | — | 0.68 | 9.12e-06 | 763 vs 1085 | 754 vs 850 | German | Mean age 99.7 | — | — | Genome-Wide Association Study | 21740922 |
rs3129063 | — | 0.67 | 4.33e-06 | 763 vs 1085 | 754 vs 850 | German | Mean age 99.7 | — | — | Genome-Wide Association Study | 21740922 |
rs3129046 | — | 0.66 | 2.21e-07 | 763 vs 1085 | 754 vs 850 | German | Mean age 99.7 | — | — | Genome-Wide Association Study | 21740922 |
rs1610742 | — | 0.66 | 3.02e-07 | 763 vs 1085 | 754 vs 850 | German | Mean age 99.7 | — | — | Genome-Wide Association Study | 21740922 |
rs1610601 | — | 0.68 | 1.98e-06 | 763 vs 1085 | 754 vs 850 | German | Mean age 99.7 | — | — | Genome-Wide Association Study | 21740922 |
rs1633063 | — | 0.68 | 3.82e-06 | 763 vs 1085 | 754 vs 850 | German | Mean age 99.7 | — | — | Genome-Wide Association Study | 21740922 |
rs11790055 | — | 1.38 | 1.49e-05 | 763 vs 1085 | 754 vs 850 | German | Mean age 99.7 | — | — | Genome-Wide Association Study | 21740922 |
rs10959258 | — | 1.36 | 1.86e-05 | 763 vs 1085 | 754 vs 850 | German | Mean age 99.7 | — | — | Genome-Wide Association Study | 21740922 |
rs9595687 | — | 0.49 | 2.09e-05 | 763 vs 1085 | 754 vs 850 | German | Mean age 99.7 | — | — | Genome-Wide Association Study | 21740922 |
rs1575892 | — | 0.45 | 9.32e-06 | 763 vs 1085 | 754 vs 850 | German | Mean age 99.7 | — | — | Genome-Wide Association Study | 21740922 |
rs16947526 | — | 0.56 | 1.23e-05 | 763 vs 1085 | 754 vs 850 | German | Mean age 99.7 | — | — | Genome-Wide Association Study | 21740922 |
rs158869 | — | 1.37 | 4.98e-06 | 763 vs 1085 | 754 vs 850 | German | Mean age 99.7 | — | — | Genome-Wide Association Study | 21740922 |
rs1528753 | — | — | 8.1e-08 | 1345 cohort + 1087 offspring | — | American | — | — | — | Genome-Wide Association Study | 17903295 |
rs2371208 | — | — | 2.6e-06 | 1345 cohort + 1087 offspring | — | American | — | — | — | Genome-Wide Association Study | 17903295 |