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polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
rs2542052 APOC3 0.001 213 old vs 216 offspring vs 258 controls Ashkenazi Jewish A Candidate Region/Gene 16602826
rs2542052 APOC3 0.0001 213 old vs 216 offspring vs 258 controls Ashkenazi Jewish A Candidate Region/Gene 16602826
rs2542052 APOC3 0.0001 213 old vs 216 offspring vs 258 controls Ashkenazi Jewish 100+ A Candidate Region/Gene 16602826
APOE e2,e3,e4 APOE 9.24 0.01 224 vs 441 Ashkenazi Jewish 75 e4 e2 Candidate Region/Gene 15621215
CTSD CTSD 1.0 224 vs 441 Ashkenazi Jewish 75 Candidate Region/Gene 15621215
ApaI IGF2 0.063 224 vs 441 Ashkenazi Jewish 75 G A Candidate Region/Gene 15621215
rs4880 SOD2 0.009 224 vs 441 Ashkenazi Jewish 75 C T Candidate Region/Gene 15621215
rs1801133 MTHFR 6.00 0.014 224 vs 441 Ashkenazi Jewish 75 T C Candidate Region/Gene 15621215
R353Q F7 0.045 224 vs 441 Ashkenazi Jewish 75 A G Candidate Region/Gene 15621215
AGT AGT 1.0 224 vs 441 Ashkenazi Jewish 75 Candidate Region/Gene 15621215
TP53 TP53 1.0 224 vs 441 Ashkenazi Jewish 75 Candidate Region/Gene 15621215
DRD4 DRD4 1.0 224 vs 441 Ashkenazi Jewish 75 Candidate Region/Gene 15621215
SLC6A4 SLC6A4 1.0 224 vs 441 Ashkenazi Jewish 75 Candidate Region/Gene 15621215
rs4537545 IL6R 3e-18 308 American, European, Ashkenazi Jewish 75.7 Candidate Region/Gene 19249341
KL-VS KLOTHO 5.88 0.004 216 vs 309 Ashkenazi Jewish 95 years and over homozygous Candidate Region/Gene 15677572
(+)2019 del ADIPOQ10 0.05 118 centenarians vs 78 unrelated young Ashkenazi Jewish 95-105 A Del/Del Candidate Region/Gene 18511746
rs5882 CETP 3.56 0.001 213 vs 258 Ashkenazi Jewish 98,2 +/- 5,3 non-GG GG Candidate Region/Gene 14559957
rs9536314 KL 0.007 216 vs 309 Ashkenazi Jewish >95 TG (genotype) Candidate Region/Gene 15677572
Y318C PMS2 0.02 390 vs 410 Ashkenazi Jewish Centenarians Candidate Region/Gene 23376243
V465A GABRR3 0.04 390 vs 410 Ashkenazi Jewish Centenarians Candidate Region/Gene 23376243
rs1801133 MTHFR 0.029 (150 m, 74 f) vs (121 m, 320 f) Ashkenazi Jewish Mean age 75 C Candidate Region/Gene 15621215
rs4880 SOD2 0.009 (150 m, 74 f) vs (121 m, 320 f) Ashkenazi Jewish Mean age 75 T Candidate Region/Gene 15621215
A/G IGF2 0.063 (150 m, 74 f) vs (121 m, 320 f) Ashkenazi Jewish Mean age 75 A, AA Candidate Region/Gene 15621215
rs429358, rs7412 APOE 0.025 (150 m, 74 f) vs (121 m, 320 f) Ashkenazi Jewish Mean age 75 e4 e2 Candidate Region/Gene 15621215
- F5 0.045 (150 m, 74 f) vs (121 m, 320 f) Ashkenazi Jewish Mean age 75 A Candidate Region/Gene 15621215
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