| polymorphism | factor | odds ratio | pvalue | initial number | replication number | Population | age of cases | shorter lived allele | longer lived allele | study type | reference |
| rs189037 | ATM | 1.85 | 0.028 | 128 vs 150 | — | Italian | — | — | — | - | 22960875 |
| rs4073591 | DEAF1 | — | 0.002618 | 1600 samples (cases and controls combined) | — | German, Italian | — | — | — | Candidate Region/Gene | 19367319 |
| rs4073590 | DEAF1 | — | 0.004259 | 1600 samples (cases and controls combined) | — | German, Italian | — | — | — | Candidate Region/Gene | 19367319 |
| rs11040489 | KRTAP5-6 | — | 0.005869 | 1600 samples (cases and controls combined) | — | German, Italian | — | — | — | Candidate Region/Gene | 19367319 |
| rs4930001 | DEAF1 | — | 0.010851 | 1600 samples (cases and controls combined) | — | German, Italian | — | — | — | Candidate Region/Gene | 19367319 |
| rs800140 | TSPAN32 | — | 0.0081 | 1600 samples (cases and controls combined) | — | German, Italian | — | — | — | Candidate Region/Gene | 19367319 |
| rs16928120 | — | — | 0.00057 | 1600 samples (cases and controls combined) | — | German, Italian | — | — | — | Candidate Region/Gene | 19367319 |
| rs1801270 | CDKN1A | 0.44 | 0.02 | 184 vs 184 | — | Italian | 100 | A | C | Candidate Region/Gene | 20126416 |
| rs1059234 | CDKN1A | 0.47 | 0.026 | 184 vs 184 | — | Italian | 100 | T | C | Candidate Region/Gene | 20126416 |
| rs3176343-rs3176344-rs3176349-rs1801270 | CDKN1A | — | 0.03972 | 184 vs 184 | — | Italian | 100 | A-G-G-A | non A-G-G-A haplotypes | Candidate Region/Gene | 20126416 |
| rs3176343-rs3176344-rs3176349-rs1801270 | CDKN1A | — | 0.00394 | 184 vs 184 | — | Italian | 100 | non G-G-G-C haplotypes | G-G-G-C | Candidate Region/Gene | 20126416 |
| rs3176343-rs3176344-rs3176349-rs1801270-rs1059234-rs876581 | CDKN1A | — | 0.02249 | 184 vs 184 | — | Italian | 100 | A-G-G-A-T-A | non A-G-G-A-T-A haplotypes | Candidate Region/Gene | 20126416 |
| rs3176343-rs3176344-rs3176349-rs1801270-rs1059234-rs876581 | CDKN1A | — | 0.00211 | 184 vs 184 | — | Italian | 100 | non G-G-G-C-C-G haplotypes | G-G-G-C-C-G | Candidate Region/Gene | 20126416 |
| (A/C)−110 | HSP70-1 | 0.40 | 0.005 | 120 vs 471 | — | Italian | 100 years and above | A | — | Candidate Region/Gene | 14501185 |
| - | CYP1A | — | 0.68 | 94 vs 418 | — | Italian | 100 years vs 46 years | — | — | Candidate Region/Gene | 11162685 |
| VNTR polymorphism | IL6 | 0.56 | 0.07 | 61 centenarians and 94 middle-aged subjects | — | Italian | 100 years vs. 52 years | — | — | Candidate Region/Gene | 17506774 |
| e4 | APOE | 0.41 | 0.05 | 79 vs 597 | — | Italian | 100+ | e4 | — | Candidate Region/Gene | 24534555 |
| HUMTHO1 (STR), haplogroups | THO, mtDNA | — | 0.045 | 202 (55m, 145 f) vs 82 (43 m, 39 f) | — | Italian | 100-105 | Long alleles + U haplogroup | — | Candidate Region/Gene | 11053670 |
| rs1799945 | HFE | — | 0.008 | 57 vs 60 | — | Italian | 100-105 | — | — | Candidate Region/Gene | 12714263 |
| - | TH | — | 0.045 | 202 vs 170 vs 82 | — | Italian | 100-105 (oldest of 3 age groups, see notes) | — | — | Candidate Region/Gene | 11053670 |
| S61712.1 (GenBank, 3` VNTR) | — | — | 0.003 | 143 (51 m, 92 f) vs 158 (77 m, 81 f) | — | Italian | 102 +/- 2 | <35 repeats | — | Candidate Region/Gene | 9050915 |
| G477T | SIRT3 | — | 0.0272 | 801 | — | Italian | 120 subject aged 100 or older | GT | TT | Candidate Region/Gene | 14580859 |
| rs429358, rs7412 | APOE | — | 0.009 | 1477 total | — | Italian | 18-109 | e4 | non-e4 | - | 16896546 |
| rs1008438 | HSPA1A | — | 0.009 | 894 total | — | Italian | 18-109 | A | C | Candidate Region/Gene | 16896546 |
| rs1008438 | HSPA1A | — | 0.02 | 894 total | — | Italian | 18-109 | C | A (applies to males) | Candidate Region/Gene | 16896546 |
