Denigma Buck Institute Health Extension

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polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
rs1800871 IL-10 — 0.0026 500 — Japanese 56.7 years; range, 19–100 years TC TT Candidate Region/Gene 16424284
rs3753645 SHC1 1.28 0.64 230 vs 180 — Japanese Mean age 100.8 +/- 1.5 T — Candidate Region/Gene 14530863
rs3753644 SHC1 1.28 0.64 230 vs 180 — Japanese Mean age 100.8 +/- 1.5 T — Candidate Region/Gene 14530863
rs2764264 FOXO3 — 0.0002 213 vs 402 — Japanese minimum 95; mean 97.9 T — Candidate Region/Gene 18765803
rs13217795 FOXO3 — 0.0006 213 vs 402 — Japanese minimum 95; mean 97.9 T — Candidate Region/Gene 18765803
rs2802292 FOXO3 — 0.0001 213 vs 402 — Japanese minimum 95; mean 97.9 T — Candidate Region/Gene 18765803
1/s 5HTT — 0.05 265 vs 225 — Japanese 101.2 S — Candidate Region/Gene 16095668
D4a mtDNA haplogroups — 0.05 112 vs 96 — Japanese Minimum age 105 non-D4a D4a Complete Mitochondrial Genome 18545700
LPA isoform LPA — 0.05 84 (cases) vs 517 — Japanese 80+ Lp(a)F, Lp(a)B — Candidate Region/Gene 11269751
rs3215173 SHC1 1.60 0.15 230 vs 180 — Japanese Mean age 100.8 +/- 1.5 G/- — Candidate Region/Gene 14530863
e4 APOE 0.35 0.001 729 vs 498 — Japanese 100+ e4 — Candidate Region/Gene 24534555
82133 G>A — — 0.0189 33 vs 39 — Japanese 90+ A — Candidate Region/Gene 15820493
HMOX1 (GT)_n repeats HMOX1 0.56 0.0027 108 vs 154 — Japanese Mean age 80.5 33 < repeats — Candidate Region/Gene 12566526
rs8191979 SHC1 — 0.38 230 vs 180 — Japanese Mean age 100.8 +/- 1.5 — — Candidate Region/Gene 14530863
rs3745548 INSR — 0.057 122 vs 122 — Japanese mean age 106.8 — — Candidate Region/Gene 15582274
rs2252673 INSR — 0.083 122 vs 122 — Japanese mean age 106.8 — — Candidate Region/Gene 15582274
rs3779501 PIK3CG — 0.139 122 vs 122 — Japanese mean age 106.8 — — Candidate Region/Gene 15582274
rs3745546 INSR — 0.168 122 vs 122 — Japanese mean age 106.8 — — Candidate Region/Gene 15582274
rs1799817 INSR — 0.205 122 vs 122 — Japanese mean age 106.8 — — Candidate Region/Gene 15582274
rs2288404 INSR — 0.277 122 vs 122 — Japanese mean age 106.8 — — Candidate Region/Gene 15582274
rs1801278 IRS1 — 0.337 122 vs 122 — Japanese mean age 106.8 — — Candidate Region/Gene 15582274
rs2305268 PIK3CB — 0.363 122 vs 122 — Japanese mean age 106.8 — — Candidate Region/Gene 15582274
rs3745544 INSR — 0.441 122 vs 122 — Japanese mean age 106.8 — — Candidate Region/Gene 15582274
rs8192678 PPARGC1A — 0.469 122 vs 122 — Japanese mean age 106.8 — — Candidate Region/Gene 15582274
rs2297627 FOXO1A — 0.495 122 vs 122 — Japanese mean age 106.8 — — Candidate Region/Gene 15582274
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