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polymorphism | factor | odds ratio | pvalue | initial number | replication number | Population | age of cases | shorter lived allele | longer lived allele | study type | reference |
---|---|---|---|---|---|---|---|---|---|---|---|
rs12778366 | SIRT1 | 0.69 | 0.025 | 1390 | — | Dutch | 36 to 79 | — | — | Candidate Region/Gene | 23505545 |
rs662 | PON1 | 1.06 | 0.11 | — | — | Danish, Dutch, French, German, Italian, Tatar | >/=80 | — | — | Candidate Region/Gene | 20362697 |
GH1 "intron SNP" | GH1 | — | 0.019 | 866 | — | Dutch | Minimum age 85 | — | — | Candidate Region/Gene | 15771611 |
rs11039149 | NR1H3 | — | 0.015 | 599 | — | Dutch | 85 years | haplotype 1 | haplotype 2 | Candidate Region/Gene | 17452725 |
rs2060793 | CYP2R1 | — | 0.04 | 1038 vs 461 | — | Dutch | 59.5 years (offspring of nonagerians) | A | — | Candidate Region/Gene | 23128285 |
rs3829251 | NADSYN1 | — | 0.6 | 1038 vs 461 | — | Dutch | 59.5 years (offspring of nonagerians) | — | — | Candidate Region/Gene | 23128285 |
rs2282679 | GC | — | 0.6 | 1038 vs 461 | — | Dutch | 59.5 years (offspring of nonagerians) | — | — | Candidate Region/Gene | 23128285 |
rs2060793 | CYP2R1 | — | 0.04 | 1038 (offspring of nonagenarians who had at least one nonagenarian sibling) vs 461 (offsprings' partners) | — | Dutch | Males: >/= 89; Females: >/= 91 | — | — | Candidate Region/Gene | 23128285 |
rs2069827 | IL6 | — | 0.064 | 1,089 vs 736 | 563 (longtitudinal study) | Danish, Dutch | 92+ Danish, 85+ Dutch | A | — | — | 22234866 |
rs970048 | Intergenic | 1.77 | 7.17e-07 | 403 vs 1670 | 3746 vs 5912 | Dutch | Mean age 94 | — | G | Genome-Wide Association Study | 21418511 |
rs2075650 | TOMM40 | 0.53 | 2.65e-06 | 403 vs 1670 | 3746 vs 5912 | Dutch | Mean age 94 | G | — | Genome-Wide Association Study | 21418511 |
rs1893132 | Intergenic | 2.07 | 3.19e-06 | 403 vs 1670 | 3746 vs 5912 | Dutch | Mean age 94 | — | A | Genome-Wide Association Study | 21418511 |
rs4110518 | Intergenic | 1.52 | 3.26e-06 | 403 vs 1670 | 3746 vs 5912 | Dutch | Mean age 94 | — | A | Genome-Wide Association Study | 21418511 |
rs9827142 | Intergenic | 1.49 | 4.88e-06 | 403 vs 1670 | 3746 vs 5912 | Dutch | Mean age 94 | — | C | Genome-Wide Association Study | 21418511 |
rs10490478 | Intergenic | 1.63 | 5.79e-06 | 403 vs 1670 | 3746 vs 5912 | Dutch | Mean age 94 | — | G | Genome-Wide Association Study | 21418511 |
rs9868286 | CCDC50 | 1.48 | 7.4e-06 | 403 vs 1670 | 3746 vs 5912 | Dutch | Mean age 94 | — | C | Genome-Wide Association Study | 21418511 |
rs11122430 | Intergenic | 1.50 | 7.65e-06 | 403 vs 1670 | 3746 vs 5912 | Dutch | Mean age 94 | — | A | Genome-Wide Association Study | 21418511 |
rs12548622 | Intergenic | 0.54 | 8.78e-06 | 403 vs 1670 | 3746 vs 5912 | Dutch | Mean age 94 | G | — | Genome-Wide Association Study | 21418511 |
rs2290889 | SYK | 2.00 | 9.14e-06 | 403 vs 1670 | 3746 vs 5912 | Dutch | Mean age 94 | — | A | Genome-Wide Association Study | 21418511 |
rs4736209 | Intergenic | 0.64 | 9.5e-06 | 403 vs 1670 | 3746 vs 5912 | Dutch | Mean age 94 | G | — | Genome-Wide Association Study | 21418511 |
rs7864625 | SYK | 2.00 | 1.01e-05 | 403 vs 1670 | 3746 vs 5912 | Dutch | Mean age 94 | — | G | Genome-Wide Association Study | 21418511 |
rs2436932 | Intergenic | 1.59 | 1.12e-05 | 403 vs 1670 | 3746 vs 5912 | Dutch | Mean age 94 | — | A | Genome-Wide Association Study | 21418511 |
rs13248142 | Intergenic | 0.55 | 1.43e-05 | 403 vs 1670 | 3746 vs 5912 | Dutch | Mean age 94 | A | — | Genome-Wide Association Study | 21418511 |
rs857788 | Intergenic | 1.41 | 1.55e-05 | 403 vs 1670 | 3746 vs 5912 | Dutch | Mean age 94 | — | G | Genome-Wide Association Study | 21418511 |
rs660100 | Intergenic | 1.48 | 1.63e-05 | 403 vs 1670 | 3746 vs 5912 | Dutch | Mean age 94 | — | G | Genome-Wide Association Study | 21418511 |