Denigma Buck Institute Health Extension

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polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
rs2070424 SOD1 — 0.77 1612 vs 1104 — German 90+ — — Candidate Region/Gene 24163049
rs13306703 — — 0.764 1612 vs 1104 — German 90+ — — Candidate Region/Gene 24163049
rs6917589 SOD2 — 0.741 1612 vs 1104 — German 90+ — — Candidate Region/Gene 24163049
rs7539614 FOXO6 1.02 0.739 1447 vs 1029 (German) 166 vs 216 (Italian) German Mean age 98.8 — — Candidate Region/Gene 21388494
rs2494738 AKT1 1.03 0.718 2996 vs 1840 — Danish, German 92-110 — — Candidate Region/Gene 22929028
rs12013673 FOXO4 0.98 0.696 1447 vs 1029 (German) 166 vs 216 (Italian) German Mean age 98.8 — — Candidate Region/Gene 21388494
rs2842980 SOD2 — 0.689 1612 vs 1104 — German 90+ — — Candidate Region/Gene 24163049
rs1007991 SOD3 — 0.679 1612 vs 1104 — German 90+ — — Candidate Region/Gene 24163049
rs4660192 FOXO6 0.97 0.663 1447 vs 1029 (German) 166 vs 216 (Italian) German Mean age 98.8 — — Candidate Region/Gene 21388494
rs2755213 FOXO1 0.95 0.626 1447 vs 1029 (German) 166 vs 216 (Italian) German Mean age 98.8 — — Candidate Region/Gene 21388494
rs699473 SOD3 — 0.613 1612 vs 1104 — German 90+ — — Candidate Region/Gene 24163049
rs4986790 TLR4 — 0.61 273 vs 594 — German Mean age 97.9 — — Candidate Region/Gene 17493663
rs5746141 SOD2 — 0.601 1612 vs 1104 — German 90+ — — Candidate Region/Gene 24163049
rs2951787 FOXO1 1.03 0.6 1447 vs 1029 (German) 166 vs 216 (Italian) German Mean age 98.8 — — Candidate Region/Gene 21388494
rs1078892 FOXO1 0.96 0.589 1447 vs 1029 (German) 166 vs 216 (Italian) German — — — Candidate Region/Gene 21388494
rs4880 SOD2 — 0.552 1612 vs 1104 — German 90+ — — Candidate Region/Gene 24163049
rs519007 FOXO3 0.93 0.55 388 vs 371 535 vs 553 German mean age 98.4 years — — Candidate Region/Gene 19196970
rs1130214 AKT1 0.97 0.544 2996 vs 1840 — Danish, German 92-110 — — Candidate Region/Gene 22929028
rs3803304 AKT1 0.97 0.544 2996 vs 1840 — Danish, German 92-110 — — Candidate Region/Gene 22929028
rs2274776 FOXO3 0.95 0.536 388 vs 371 535 vs 553 German mean age 98.4 years — — Candidate Region/Gene 19196970
rs11585393 FOXO6 1.04 0.531 1447 vs 1029 (German) 166 vs 216 (Italian) German Mean age 98.8 — — Candidate Region/Gene 21388494
rs4998557 SOD1 — 0.52 1612 vs 1104 — German 90+ — — Candidate Region/Gene 24163049
rs17630266 FOXO1 1.11 0.51 1447 vs 1029 (German) 166 vs 216 (Italian) German Mean age 98.8 — — Candidate Region/Gene 21388494
rs2494731 AKT1 1.03 0.503 2996 vs 1840 — Danish, German 92-110 — — Candidate Region/Gene 22929028
rs2494748 AKT1 0.95 0.466 1383 vs 736 — Danish, German 92-110 — — Candidate Region/Gene 22929028