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| polymorphism | factor | odds ratio | pvalue | initial number | replication number | Population | age of cases | shorter lived allele | longer lived allele | study type | reference |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 56 SNPs - CYP2C gene family | CYP2C gene family: CYP2C8, CYP2C9, CYP2C18, CYP2C19 | — | 1.0 | 1,384 vs 945 | — | German | Mean age 98.8 | — | — | Candidate Region/Gene | 21798861 |
| rs3758391 | SIRT1 | — | 1.0 | 386 vs 640 vs 547 | — | German | Mean age 101 | — | — | Candidate Region/Gene | 16257164 |
| rs1885472 | SIRT1 | — | 1.0 | 386 vs 640 vs 547 | — | German | Mean age 101 | — | — | Candidate Region/Gene | 16257164 |
| rs2273773 | SIRT1 | — | 1.0 | 386 vs 640 vs 547 | — | German | Mean age 101 | — | — | Candidate Region/Gene | 16257164 |
| rs10997870 | SIRT1 | — | 1.0 | 386 vs 640 vs 547 | — | German | Mean age 101 | — | — | Candidate Region/Gene | 16257164 |
| rs2234975 | SIRT1 | — | 1.0 | 386 vs 640 vs 547 | — | German | Mean age 101 | — | — | Candidate Region/Gene | 16257164 |
| rs1801274 | FCGR2A | — | 1.0 | 408 vs 446 vs 454 | — | German | Centenarians | — | — | Candidate Region/Gene | 16893392 |
| length (STR polymorphism) | TH | — | 1.0 | 196 vs 358 | 471 vs 462 | German | (in replication) 96-110 years | — | — | Candidate Region/Gene | 21407269 |
| rs1799814 | CYP1A1 | 1.16 | 1.0 | 205 vs 294 | — | German | 80-89; reference group: 17-79 | — | — | - | 15177664 |
| rs1041740 | SOD1 | — | 0.998 | 1612 vs 1104 | — | German | 90+ | — | — | Candidate Region/Gene | 24163049 |
| rs12876443 | FOXO1 | 1.00 | 0.989 | 1447 vs 1029 (German) | 166 vs 216 (Italian) | German | Mean age 98.8 | — | — | Candidate Region/Gene | 21388494 |
| rs5981072 | FOXO4 | 0.98 | 0.976 | 1447 vs 1029 (German) | 166 vs 216 (Italian) | German | Mean age 98.8 | — | — | Candidate Region/Gene | 21388494 |
| rs8192287 | SOD3 | — | 0.955 | 1612 vs 1104 | — | German | 90+ | — | — | Candidate Region/Gene | 24163049 |
| rs2536512 | SOD3 | — | 0.942 | 1612 vs 1104 | — | German | 90+ | — | — | Candidate Region/Gene | 24163049 |
| rs1571631 | FOXO3 | 0.99 | 0.872 | 388 vs 371 | 535 vs 553 | German | mean age 98.4 years | — | — | Candidate Region/Gene | 19196970 |
| rs6690527 | FOXO6 | 1.01 | 0.867 | 1447 vs 1029 (German) | 166 vs 216 (Italian) | German | Mean age 98.8 | — | — | Candidate Region/Gene | 21388494 |
| rs7855 | SOD2 | — | 0.842 | 1612 vs 1104 | — | German | 90+ | — | — | Candidate Region/Gene | 24163049 |
| rs1317557 | FOXO6 | 1.04 | 0.824 | 1447 vs 1029 (German) | 166 vs 216 (Italian) | German | Mean age 98.8 | — | — | Candidate Region/Gene | 21388494 |
| rs6693260 | FOXO6 | 0.98 | 0.824 | 1447 vs 1029 (German) | 166 vs 216 (Italian) | German | Mean age 98.8 | — | — | Candidate Region/Gene | 21388494 |
| rs2498796 | AKT1 | 0.99 | 0.788 | 2996 vs 1840 | — | Danish, German | 92-110 | — | — | Candidate Region/Gene | 22929028 |
| rs3803304 | AKT1 | 0.99 | 0.784 | 2702 vs 1840 | — | Danish, German | 92-110 | — | — | Candidate Region/Gene | 22929028 |
| rs1056836 | CYP1B1 | 0.63 | 0.78 | 205 vs 294 | — | German | 80-89; reference group: 17-79 | — | — | - | 15177664 |
| rs9603776 | FOXO1 | 1.05 | 0.778 | 1447 vs 1029 (German) | 166 vs 216 (Italian) | German | Mean age 98.8 | — | — | Candidate Region/Gene | 21388494 |
| rs2701893 | FOXO1 | 0.98 | 0.772 | 1447 vs 1029 (German) | 166 vs 216 (Italian) | German | Mean age 98.8 | — | — | Candidate Region/Gene | 21388494 |
| rs2755209 | FOXO1 | 0.98 | 0.77 | 1447 vs 1029 (German) | 166 vs 216 (Italian) | German | Mean age 98.8 | — | — | Candidate Region/Gene | 21388494 |