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polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
rs1042719 ADRB2 1.29 1.29 384 vs 384 579 vs 644 Chinese Mean age 102.1±0.20 G C Candidate Region/Gene 23020224
12358G,5417A,10873T mtDNA — 0.058 463 vs 1389 — Chinese >/=95 — — Mitochondrial Haplogroup 19641616
rs4646994 ACE — 0.05 4000 — Chinese Minimum age 65 DD — Candidate Region/Gene 22456784
rs1061581 HSPA1B — 0.05 191 vs 53 — Chinese >90 A G Candidate Region/Gene 19840767
rs2266968 MAPK1 — 0.048 384 vs 384 579 vs 644 Chinese Mean age 102.1±0.20 — — Candidate Region/Gene 23020224
rs429358 + rs7412 APOE — 0.04 1236 vs 326 — Chinese 60+ e4 non-e4 Candidate Region/Gene 9792194
XbaI APOB 1.30 0.03 191 (case) vs 53 — Chinese > 90 baseline, Mean age 97 +/- 3 — X+X+ Candidate Region/Gene 17393087
4491A,3705G,10400T mtDNA — 0.027 463 vs 1389 — Chinese >/=95 — — Mitochondrial Haplogroup 19641616
rs3928306 MT-RNR2 0.49 0.027 98 vs 117 — Chinese 90–100 A — Candidate Region/Gene 18759861
rs3758391 SIRT1 1.45 0.026 246 vs 236 — Chinese 71.2±7.1 years T — Candidate Region/Gene 20633545
rs3758391 SIRT1 1.45 0.026 246 vs 236 — Chinese 60-90 — C Candidate Region/Gene 20633545
9 mtDNA haplogroups mtDNA haplogroup 0.38 0.025 98 vs. 117 — Chinese 90-100 years old J non-J - 18759861
Haplogroup J — 0.38 0.025 98 vs 117 — Chinese 90–100 — — Candidate Region/Gene 18759861
rs1061581-rs1043618-rs2227956 — 3.46 0.025 191 vs 53 — Chinese >90 non A-G-C or non A-C-T haplotypes A-G-C Candidate Region/Gene 19840767
rs4746720 — 1.35 0.022 246 vs 236 — Chinese 60-90 — C Candidate Region/Gene 20633545
rs4746720 SIRT1 1.35 0.022 246 vs 236 — Chinese 71.2±7.1 years T — Candidate Region/Gene 20633545
HLA-C phenotype HLA-C 0.49 0.02 201 vs 211 — Chinese >93 Cw3, Cw6. Cw7 — Candidate Region/Gene 9147371
5417A,10873T mtDNA — 0.018 463 vs 1389 — Chinese >/=95 — — Mitochondrial Haplogroup 19641616
rs1061581-rs1043618-rs2227956 — 4.51 0.016 191 vs 53 — Chinese >90 non A-G-C or non A-C-T haplotypes A-C-T Candidate Region/Gene 19840767
rs1042718 ADRB2 1.27 0.014 384 vs 384 579 vs 644 Chinese Mean age 102.1±0.20 C A Candidate Region/Gene 23020224
E4 APOE — 0.013 35 vs 125 — Chinese 90 years or over — — Candidate Region/Gene 11780357
apoE haplotypes APOE — 0.013 35 old vs 71 young vs 54 MI patients — Chinese 90 apoE4 ApT4 Candidate Region/Gene 11780357
apoE haplotypes APOE — 0.013 35 old vs 71 young vs 54 MI patients — Chinese 90 apoE4 — Candidate Region/Gene 11780357
APOE4 APOE — 0.013 35 vs 125 — Chinese 90 years or over High E4 frequency — Candidate Region/Gene 11780357
1376G/T;1388G/A;95A/G;871G/A;1024C/T;1360C/T;392 G/T G6PD 6.30 0.013 173 total (see notes) — Chinese >80 — — Candidate Region/Gene 17077204
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