| polymorphism | factor | odds ratio | pvalue | initial number | replication number | Population | age of cases | shorter lived allele | longer lived allele | study type | reference |
| APOB XbaI − SI000565Q | APOB | — | 0.006 | 191 (case) vs 53 (initial) | — | Chinese | > 90 baseline, Mean age 97 +/- 3 | X+ - Short | X+ - Medium | Candidate Region/Gene | 17393087 |
| mtDNA haplogroups | mtDNA | 7.56 | 0.0015 | 74 vs 187 | — | Amish | >80 years | non-X | X | Mitochondrial Haplogroup | 21750925 |
| REN polymorphism - mtDNA | mtDNA | 3.27 | 0.006 | 157 | — | Italian | 100+ | — | REN10 - mtDNA haplogroup H | Candidate Region/Gene | 11938442 |
| 9 mtDNA haplogroups | mtDNA haplogroup | 0.38 | 0.025 | 98 vs. 117 | — | Chinese | 90-100 years old | J | non-J | - | 18759861 |
| mtDNA haplogroups | mtDNA | 0.40 | 0.0003 | 74 vs 187 | — | Amish | >80 years | J | non-J | Mitochondrial Haplogroup | 21750925 |
| rs11568820-rs4516035-rs10735810-rs1544410-rs17878969 | VDR | 11.50 | 0.024 | 104 vs 114 | — | Caucasian, Spaniard | >85 | G-G-C-G-S | non G-G-C-G-S haplotypes | Candidate Region/Gene | 20407924 |
| rs1800796-(−373(A)n(T)m)-rs1800795 | IL6 | — | 0.07 | 1710 total | — | Danish | 47-100 | G-(−373(A)8(T)12)-C | non G-(−373(A)8(T)12)-C haplotypes | Candidate Region/Gene | 15130757 |
| rs3176343-rs3176344-rs3176349-rs1801270-rs1059234-rs876581 | CDKN1A | — | 0.02249 | 184 vs 184 | — | Italian | 100 | A-G-G-A-T-A | non A-G-G-A-T-A haplotypes | Candidate Region/Gene | 20126416 |
| rs3176343-rs3176344-rs3176349-rs1801270 | CDKN1A | — | 0.03972 | 184 vs 184 | — | Italian | 100 | A-G-G-A | non A-G-G-A haplotypes | Candidate Region/Gene | 20126416 |
| mtDNA haplogroups | mtDNA | — | 0.027 | 138 | — | Spaniard | Minimum age 85 | non-J | J | Mitochondrial Haplogroup | 18931934 |
| rs11279109 - APOB XbaI - SI000565Q | APOB | — | 0.044 | 191 (case) vs 53 | — | Chinese | > 90 baseline, Mean age 97 +/- 3 | D - X+ - Short | I - X+ - Medium; D - X- - Long; D - X- - Medium | Candidate Region/Gene | 17393087 |
| HP 1/2 | HP | 1.27 | 0.0194 | 1072 total | — | Italian | >88 | HP*2 | HP*1 | Candidate Region/Gene | 21147083 |
| rs915179-rs2485662-rs4641-rs1468772 | LMNA | 1.56 | 2.5e-05 | 873 vs 443 | New England Centenarian Study (NECS) (N = 738), (ii) the Southern Italian Centenarian Study (SICS) (N = 905), (iii) France (N = 1103), and (iv) the Einstein Ashkenazi Longevity Study (N = 702) | American, Caucasian | Mean age 101.5 | — | GTCT | Candidate Region/Gene | 22340368 |
| rs1800896 - rs1800629 | IL10 | — | 0.038 | 174 vs 224 | — | Italian | >100 | — | GG-GG (only in men) | Candidate Region/Gene | 12676903 |
| Cdx2–GATA haplotypes | VDR | — | 0.05 | 923 | — | Dutch | Mean age 75.7 | GG | GA, AA | Candidate Region/Gene | 21051524 |
| rs1544410-rs17878969 | VDR | 15.30 | 0.001 | 104 vs 114 | — | Caucasian, Spaniard | >85 | non G-S haplotypes | G-S | Candidate Region/Gene | 20407924 |
| rs3176343-rs3176344-rs3176349-rs1801270-rs1059234-rs876581 | CDKN1A | — | 0.00211 | 184 vs 184 | — | Italian | 100 | non G-G-G-C-C-G haplotypes | G-G-G-C-C-G | Candidate Region/Gene | 20126416 |
| rs3176343-rs3176344-rs3176349-rs1801270 | CDKN1A | — | 0.00394 | 184 vs 184 | — | Italian | 100 | non G-G-G-C haplotypes | G-G-G-C | Candidate Region/Gene | 20126416 |
| rs1061581 - rs1008438 - rs2227956 | Hsp70Ba | 0.55 | 0.015 | 168 cases | — | Danish | Mean age 92.8 +/- 0.4 | — | G-C-T (haplotype) | Candidate Region/Gene | 20388090 |
| rs2107538-rs2280789 | RANTES | — | 0.04 | 104 vs 110 | — | Spaniard | Mean age 89.6 | non G-C haplotypes | G-C | Candidate Region/Gene | 22265023 |
| rs429358, rs7412 | APOE | — | 0.001 | 179 vs 615 | — | Finn | Mean age 100 | e4 | e2, e3 | Candidate Region/Gene | 8018664 |
| APOE polymorphism | APOE | 3.26 | 0.001 | 64 vs 1344 | — | Italian | 100+ | e4 | e2 | Candidate Region/Gene | 16960022 |
| APOE polymorphism | APOE | — | 0.0001 | 291 vs 589 | — | Finn | Mean age 97.5 | e4 | e2 | Candidate Region/Gene | 16487435 |
| APOE haplotype - rs1346044 | APOE | — | 0.0001 | 175 vs 178 | — | Finn | 100.8 | e4 | e2 | Candidate Region/Gene | 10069711 |
| APOE polymorphism | APOE | 0.38 | 0.002 | 200 (cases) vs 539 | — | Italian | >88 | e4 | e2 | Candidate Region/Gene | 21703254 |
