| polymorphism | factor | odds ratio | pvalue | initial number | replication number | Population | age of cases | shorter lived allele | longer lived allele | study type | reference |
| IL10 haplotypes | IL10 | — | 0.05 | 237 vs 90 | — | Turkish | Age range: 65-99 | — | −1082G, −819C, −592C | Candidate Region/Gene | 21299522 |
| IL10 haplotypes | IL10 | — | 0.05 | 60 vs 60 | — | Bulgarian | Age range: 65-99 | — | −1082G, −819C, -592C | Candidate Region/Gene | 21299522 |
| TNF haplotypes | TNF | — | 0.01 | 60 vs 50 | — | Bulgarian | Age range: 65-99 | — | −1031 C/C, −863 C/A, −857 C/C, −308 G/G, +489 G/G | Candidate Region/Gene | 21299522 |
| AAT M/Z/S | AAT | 0.18 | 1e-07 | 143 vs 255 vs 127 | — | Italian | Centenarians | M, S | Z | Candidate Region/Gene | 17048073 |
| HFE C282Y | HFE | — | 7.2e-07 | 35 vs 106 | — | | 91-105 (< 50 versus >90) | C | Y | Candidate Region/Gene | 11857056 |
| XbaI | APOB | 1.30 | 0.03 | 191 (case) vs 53 | — | Chinese | > 90 baseline, Mean age 97 +/- 3 | — | X+X+ | Candidate Region/Gene | 17393087 |
| mtDNA haplogroups | mtDNA | 7.56 | 0.0015 | 74 vs 187 | — | Amish | >80 years | non-X | X | Mitochondrial Haplogroup | 21750925 |
| rs2227956 | HSPA1L | — | 0.01 | 191 vs 53 | — | Chinese | >90 | TC | TT/CC | Candidate Region/Gene | 19840767 |
| rs1800871 | IL-10 | — | 0.0026 | 500 | — | Japanese | 56.7 years; range, 19–100 years | TC | TT | Candidate Region/Gene | 16424284 |
| G477T | SIRT3 | — | 0.0272 | 801 | — | Italian | 120 subject aged 100 or older | GT | TT | Candidate Region/Gene | 14580859 |
| rs1061170 | CFH | 1.78 | 0.005 | 491 with follow-up during 4 years | — | Finn | >90 | — | TT | Candidate Region/Gene | 19000922 |
| rs9330200 | TUBB4B | — | 6e-53 | 5036 | — | American | 28-70 | AA, AT | TT | Genome-Wide Association Study | 22174011 |
| rs9536314 | KL | — | 0.007 | 216 vs 309 | — | Ashkenazi Jewish | >95 | — | TG (genotype) | Candidate Region/Gene | 15677572 |
| rs1805415 | PARP1 | 0.66 | 0.001 | 479 vs 900 | 388 vs 364 | African American, Caucasian | — | G,C | T | Candidate Region/Gene | 19249341 |
| rs2755209 | FOXO1 | 0.80 | 0.0046 | 761 vs 1056 | 350 vs 350 | Chinese | mean age 102.3 | C | T | Candidate Region/Gene | 19793722 |
| rs2755213 | FOXO1 | 0.75 | 7.4e-05 | 761 vs 1056 | 350 vs 350 | Chinese | mean age 102.3 | C | T | Candidate Region/Gene | 19793722 |
| rs2802292 | FOXO3 | 1.36 | 2.9e-05 | 761 vs 1056 | 350 vs 350 | Chinese | mean age 102.3 | G | T | Candidate Region/Gene | 19793722 |
| rs3800358 | BTBD9 | — | 0.00541 | 1173 vs 570 | — | American | 85-100 | — | T | Genome-Wide Association Study | 22533364 |
| rs139170 | PARVG | — | 0.00332 | 1173 vs 570 | — | American | 85-100 | — | T | Genome-Wide Association Study | 22533364 |
| rs4648884 | RUNX3 | — | 0.00992 | 1173 vs 570 | — | American | 85-100 | — | T | Genome-Wide Association Study | 22533364 |
| rs10937739 | PPP2R2C | — | 0.00404 | 1173 vs 570 | — | American | 85-100 | — | T | Genome-Wide Association Study | 22533364 |
| rs13053175 | RAC2 | — | 0.00697 | 1173 vs 570 | — | American | 85-100 | — | T | Genome-Wide Association Study | 22533364 |
| rs4148544 | ABCC4 | — | 0.00977 | 1173 vs 570 | — | American | 85-100 | — | T | Genome-Wide Association Study | 22533364 |
| rs2370413 | CACNA1C | — | 0.0011 | 1173 vs 570 | — | American | 85-100 | — | T | Genome-Wide Association Study | 22533364 |
| rs2826891 | NCAM2 | — | 0.00402 | 1173 vs 570 | — | American | 85-100 | — | T | Genome-Wide Association Study | 22533364 |
