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| polymorphism | factor | odds ratio | pvalue | initial number | replication number | Population | age of cases | shorter lived allele | longer lived allele | study type | reference |
|---|---|---|---|---|---|---|---|---|---|---|---|
| rs4946936 | FOXO3 | 1.40 | 1.8e-05 | 761 vs 1056 | 350 vs 350 | Chinese | mean age 102.3 | T | C | Candidate Region/Gene | 19793722 |
| rs1042718-rs1042719 | ADRB2 | 0.63 | 1.86e-05 | 384 vs 384 | 579 vs 644 | Chinese | Mean age 102.1±0.20 | G-C | A-C | Candidate Region/Gene | 23020224 |
| rs2802292 | FOXO3 | 1.36 | 2.9e-05 | 761 vs 1056 | 350 vs 350 | Chinese | mean age 102.3 | G | T | Candidate Region/Gene | 19793722 |
| rs2755213 | FOXO1 | 0.75 | 7.4e-05 | 761 vs 1056 | 350 vs 350 | Chinese | mean age 102.3 | C | T | Candidate Region/Gene | 19793722 |
| rs2253310 | FOXO3 | 1.35 | 7.9e-05 | 761 vs 1056 | 350 vs 350 | Chinese | mean age 102.3 | C | G | Candidate Region/Gene | 19793722 |
| rs4746720 | SIRT1 | 2.10 | 0.0001 | 223 vs 277 | — | Chinese | Average age 93 | CC, TT | CT | Candidate Region/Gene | 23450480 |
| SI000565Q | APOB | — | 0.0005 | 191 (case) vs 53 (initial) | — | Chinese | > 90 baseline, Mean age 97 +/- 3 | Short | Long | Candidate Region/Gene | 17393087 |
| HLA-A phenotype | HLA-A | 1.95 | 0.002 | 201 vs 211 | — | Chinese | 22 centenarians + 179 nonagenarians (mean age 93 ±1.04) | A9 | A30 | Candidate Region/Gene | 9147371 |
| STR variation | CSF1TPO | — | 0.003 | 60 vs 250 | — | Chinese | >90 | low variation in STRs | high variation in STRs | - | 20582731 |
| rs2291727 | ADCY6 | — | 0.003 | 384 vs 384 | 579 vs 644 | Chinese | Mean age 102.1±0.20 | — | — | Candidate Region/Gene | 23020224 |
| rs28359172 | MT-ND5 | 0.30 | 0.003 | 98 vs 117 | — | Chinese | 90–100 | G | — | Candidate Region/Gene | 18759861 |
| mtDNA haplogroups | mtDNA | 2.01 | 0.003 | 367 vs 371 | — | Chinese | Mean age 94.4 | non-F | F | Mitochondrial Haplogroup | 21945877 |
| rs189037 (genotype) | ATM | — | 0.004 | 875 (280 m, 595 f) vs 886 (491 m, 395 f) | — | Chinese | Mean age 94,6, healthy | — | CT (Article); GA (ENSEMBL) | Candidate Region/Gene | 20816691 |
| rs2755209 | FOXO1 | 0.80 | 0.0046 | 761 vs 1056 | 350 vs 350 | Chinese | mean age 102.3 | C | T | Candidate Region/Gene | 19793722 |
| rs2227956 | HSPA1L | — | 0.01 | 191 vs 53 | — | Chinese | >90 | TC | TT/CC | Candidate Region/Gene | 19840767 |
| E4 | APOE | — | 0.013 | 35 vs 125 | — | Chinese | 90 years or over | — | — | Candidate Region/Gene | 11780357 |
| apoE haplotypes | APOE | — | 0.013 | 35 old vs 71 young vs 54 MI patients | — | Chinese | 90 | apoE4 | ApT4 | Candidate Region/Gene | 11780357 |
| apoE haplotypes | APOE | — | 0.013 | 35 old vs 71 young vs 54 MI patients | — | Chinese | 90 | apoE4 | — | Candidate Region/Gene | 11780357 |
| APOE4 | APOE | — | 0.013 | 35 vs 125 | — | Chinese | 90 years or over | High E4 frequency | — | Candidate Region/Gene | 11780357 |
| 1376G/T;1388G/A;95A/G;871G/A;1024C/T;1360C/T;392 G/T | G6PD | 6.30 | 0.013 | 173 total (see notes) | — | Chinese | >80 | — | — | Candidate Region/Gene | 17077204 |
| rs1042718 | ADRB2 | 1.27 | 0.014 | 384 vs 384 | 579 vs 644 | Chinese | Mean age 102.1±0.20 | C | A | Candidate Region/Gene | 23020224 |
| rs1061581-rs1043618-rs2227956 | — | 4.51 | 0.016 | 191 vs 53 | — | Chinese | >90 | non A-G-C or non A-C-T haplotypes | A-C-T | Candidate Region/Gene | 19840767 |
| 5417A,10873T | mtDNA | — | 0.018 | 463 vs 1389 | — | Chinese | >/=95 | — | — | Mitochondrial Haplogroup | 19641616 |
| HLA-C phenotype | HLA-C | 0.49 | 0.02 | 201 vs 211 | — | Chinese | >93 | Cw3, Cw6. Cw7 | — | Candidate Region/Gene | 9147371 |
| rs4746720 | — | 1.35 | 0.022 | 246 vs 236 | — | Chinese | 60-90 | — | C | Candidate Region/Gene | 20633545 |