Longevity Variant Database

Narrow results by variant, study, or associated fields (e.g. gene symbol ADRB2):

Use ontology terms to further narrow results (e.g. aging, insulin, etc.):


  • Variant effect: + -
  • Variant type: + -

  • 1 2 3 4 5 6 7 8 9 10 11 12
    13 14 15 16 17 18 19 20 21 X Y MT
    Export results (Download)

    Populations | Study Types | Variant Types



    LVDB_word_cloud.png
    logo.png
    variants.jpg
    polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
    rs5882 CETP 0.63 Multiethnic Meta-Analysis 24468472
    rs708272 CETP 0.53 Multiethnic Meta-Analysis 24468472
    MTP -493G/T MTP 0.854 Chinese - 23273182
    rs662 PON1 1.06 0.33 Irish >/=80 Candidate Region/Gene 20362697
    rs662 PON1 1.03 0.55 Irish >/=100 Candidate Region/Gene 20362697
    rs662 PON1 1.06 0.11 Danish, Dutch, French, German, Italian, Tatar >/=80 Candidate Region/Gene 20362697
    rs11279109 - APOB XbaI - SI000565Q APOB 0.044 191 (case) vs 53 Chinese > 90 baseline, Mean age 97 +/- 3 D - X+ - Short I - X+ - Medium; D - X- - Long; D - X- - Medium Candidate Region/Gene 17393087
    Cdx2-GATA haplotype 1 allele Vitamin D receptor 0.78 935 participants Dutch mean age = 75.7 years Candidate Region/Gene 21051524
    rs12696304 TERC 0.248 1013 total Danish Candidate Region/Gene 22136229
    ACE genotype ACE 0.716 102 vs 7232 Korean Mean age 102 Candidate Region/Gene 12634288
    rs2282679 GC 0.6 1038 vs 461 Dutch 59.5 years (offspring of nonagerians) Candidate Region/Gene 23128285
    HP*1 F/S HP 0.82 0.33 1072 total Italian >88 Candidate Region/Gene 21147083
    rs2764264 FOXO3 0.05 1089 vs 736 Danish 92–93 T Candidate Region/Gene 20849522
    rs7762395 FOXO3 0.05 1089 vs 736 Danish 92–93 G Candidate Region/Gene 20849522
    rs13217795 FOXO3 0.05 1089 vs 736 Danish 92–93 T Candidate Region/Gene 20849522
    rs9400239 FOXO3 0.05 1089 vs 736 Danish 92–93 C Candidate Region/Gene 20849522
    rs9398172 FOXO3 0.05 1089 vs 736 Danish 92–93 A Candidate Region/Gene 20849522
    rs479744 FOXO3 0.05 1089 vs 736 Danish 92–93 (can't figure out using ensemble and NCBI) Candidate Region/Gene 20849522
    rs266729 ADIPQO 0.635 110 vs 120 Jordanian mean age 90.2 years G C Candidate Region/Gene 20201642
    rs2241766 ADIPQO 0.164 110 vs 120 Jordanian mean age 90.2 years G T Candidate Region/Gene 20201642
    R353Q FVII 0.61 113 vs 100 Scottish 96 years vs 32 years - 10744171
    IVS7 FVII 0.69 113 vs 100 Scottish 96 vs 32 - 10744171
    rs1800629 TNF 1.0 119 vs 118 Jordanian Mean age 90.2 Candidate Region/Gene 20518833
    rs708272 CETP 1.0 12 vs 190 vs 105 Greek 99-111 Candidate Region/Gene 23389097
    rs5882 CETP 1.0 12 vs 190 vs 105 Greek 99-111 Candidate Region/Gene 23389097
    • Page 1 of 22
    • 25 of 543 variants

    The Longevity Variant Database (LVDB) is a collaborative effort to catalogue all published genetic variants relevant to human longevity.

    The project is directed by the Health Extension Research Foundation [http://www.healthextension.co/about/], and the online content is managed by the members of the Global Computing Initiative.

    LVDB is driven by an international collaboration of scientists, programmers, and volunteers, including Joe Betts-LaCroix, Kristen Fortney, Daniel Wuttke, Eric K. Morgen, Nick Schaum, John M. Adams, Jessica Choi, Barry Goldberg, Amir Levine, Maria Litovchenko, Aiste Narkeviciute, Emily Quist, Navneet Ramesh, Justin Rebo, Dmitri Shytikov, and Jimi Vyas. o


    Suggest a new study Report a database issue