-308G/A

Polymorphism: -308G/A


Location: 6p21.3

Factor:
- Symbol: TNF
- Name: tumor necrosis factor
- Entrez ID: 7124
- Ensembl ID: ENSG00000232810

Factors:

TNF tumor necrosis factor ( 7124 / ENSG00000232810 )

Description:

Signf. applies to heterozygote genotype G/A

Ethnicity: Mexican
Age of cases: 86.2
Shorter lived allele: G

Statistics
- Number of cases/controls: 71 vs 99 (initial)
- Odds ratio: 0.33
- p-value: 0.001 [0.001]
- Significant: Yes

Study Design
- Classifications: Longevity-Associated
- Study type: Candidate Region/Gene
- Technology: PCR fragment amplified using NcoI restriction enzyme, loaded on 2% agarose

Reference:
16269080: Human leukocyte antigen class I, class II, and tumor necrosis factor-alpha polymorphisms in a healthy elder Mexican Mestizo population.

Choice: Curate
Created: July 2, 2013, 2:47 a.m.
Updated: Aug. 8, 2014, 1:06 p.m.

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