The increased frequency DQA10101=0104 can be explained by a LD with DRBl1401 or vice versa, which was also significantly frequent in them, because DRB11401-DQB10503-DQA10104 is one of the prominent haplotypes in Okinawan Japanese. Alleles that were significant before but not after corrected P value test: Decreased in centenarians (HLA-DQA10102, HLA-DQA1*0103). Note: related to rs6457617?
odds_ratio = RR = 1.739 (could not convert string to float: RR = 1.739)
Ethnicity:Okinawan Age of cases: Mean age 102.3 +/- 1.9 years Shorter lived allele: non-HLA-DQA1*0101=0104 alleles Longer lived allele: HLA-DQA1*0101=0104
Statistics - Number of cases/controls: 120 vs 129 (initial)
- p-value:
0.04
[0.04]
- Significant: Yes
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