rs1800795

Polymorphism: rs1800795
rs1800795 ( SNPedia | 23andMe )

Location: 7p21

Factor:
- Symbol: IL-6
- Name: interleukin 6 (interferon, beta 2)
- Entrez ID: 3569
- Ensembl ID: ENSG00000136244

Factors:
  • IL-6 interleukin 6 (interferon, beta 2) ( 3569 / ENSG00000136244 )


  • Description:

    Frequency of G allele higher in survivors (mortality at ages 90-95 from initial cohort of octogenerians).

    Ethnicity: Finn
    Age of cases: 90-95
    Shorter lived allele: C
    Longer lived allele: G

    Statistics
    - Number of cases/controls: 285 (initial)
    - p-value: 0.018 [0.018]
    - Significant: Yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Candidate Region/Gene
    - Technology: Not described

    Reference:
    15664628: Interleukin-6 -174G/C polymorphism and longevity: a follow-up study.

    Choice: Curate_Johnny
    Created: July 1, 2013, 10:06 a.m.
    Updated: Aug. 8, 2014, 1:05 p.m.

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