rs12740413

Polymorphism: rs12740413
rs12740413 ( SNPedia | 23andMe )

Variant Type: SNP
Location: 1p36.13

Factor:
- Symbol: ARHGEF19
- Name: Rho guanine nucleotide exchange factor (GEF) 19
- Entrez ID: 128272
- Ensembl ID: ENSG00000142632

Factors:
  • ARHGEF19 Rho guanine nucleotide exchange factor (GEF) 19 ( 128272 / ENSG00000142632 )


  • Description:

    P value for association with age at death.

    Ethnicity: American, British
    Age of cases: Age range 50-108; mean age at death 80.2
    Shorter lived allele: T
    Longer lived allele: C
    Finding: Positive

    Statistics
    - Number of cases/controls: 1364 (initial)
    - Odds ratio type: N/A
    - p-value: 1.3e-05 [0.000013]
    - Significant: Nominally yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Genome-Wide Association Study
    - Technology: Illumina 300, Illumina 610

    Reference:
    22445811: Genetic variants influencing human aging from late-onset Alzheimer's disease (LOAD) genome-wide association studies (GWAS).

    Choice: Clean
    Created: Aug. 14, 2013, 1:16 a.m.
    Updated: Aug. 8, 2014, 1:05 p.m.

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