rs2075650

Polymorphism: rs2075650
rs2075650 ( SNPedia | 23andMe )

Variant Type: SNP
Location: 19q13.2

Factor:
- Symbol: APOE
- Name: apolipoprotein E
- Entrez ID: 348
- Ensembl ID: ENSG00000130203

Factors:
  • APOE apolipoprotein E ( 348 / ENSG00000130203 )


  • Description:

    P value reported is uncorrected, but association did remain significant after correcting for multiple testing. P value for association with age at death.

    Ethnicity: American, British
    Age of cases: Age range 50-108; mean age at death 80.2
    Shorter lived allele: C
    Longer lived allele: T
    Finding: Positive

    Statistics
    - Number of cases/controls: 1364 (initial)
    - p-value: 0.000527 [0.000527]
    - Significant: Yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Candidate Region/Gene
    - Technology: Illumina 300, Illumina 610

    Reference:
    22445811: Genetic variants influencing human aging from late-onset Alzheimer's disease (LOAD) genome-wide association studies (GWAS).

    Choice: Clean
    Created: Aug. 14, 2013, 12:50 a.m.
    Updated: Aug. 8, 2014, 1:06 p.m.

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