rs4420638

Polymorphism: rs4420638
rs4420638 ( SNPedia | 23andMe )

Location: 19q13.31

Factor:
- Symbol: APOC1
- Name: apolipoprotein C-I
- Entrez ID: 341
- Ensembl ID: ENSG00000130208


Description:

In LD with the APOE allele ɛ4.

Ethnicity: German
Age of cases: Mean age 99.7
Shorter lived allele: G

Statistics
- Number of cases/controls: 763 vs 1085 (initial) | 754 vs 850 (replication)
- Odds ratio: 0.53
- p-value: 1.8e-10
- Significant: Yes

Study Design
- Classifications: Longevity-Associated
- Study type: Genome-Wide Association Study
- Technology: Affymetrix Genome-Wide Human SNP Array 6.0

Reference:
21740922: A genome-wide association study confirms APOE as the major gene influencing survival in long-lived individuals.

Choice: Curate
Created: Aug. 20, 2013, 7:43 a.m.
Updated: Aug. 8, 2014, 1:05 p.m.

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