Men with the TAFI −438 A/A genotype had decreased mortality due to all causes, and lived, on average, 0.9 more years of life, or 1.1 more years of healthy life, than men with the −438 G allele. The effects of TAFI −438 G/A in women were smaller and not statistically significant. Detailed OR information is as follows: 0.53 (0.32–0.87).
Ethnicity:American,
Caucasian Age of cases: 65+ Shorter lived allele: G (men) Finding: Positive
Statistics - Number of cases/controls: 2224 (initial)
- Odds ratio: 0.53 - p-value:
0.003
[0.003]
- Significant: Yes
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