AAT M/Z/S
Polymorphism: AAT M/Z/S
Location: 14q32.1
Factor:
- Symbol: AAT
- Name: serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
- Entrez ID: 5265
- Ensembl ID: ENSG00000197249
Factors:
AAT
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
(
5265
/
ENSG00000197249
)
Age of cases: Minimum age 99
Shorter lived allele: M, S
Statistics
- Number of cases/controls: 143 vs 255 (initial)
- Odds ratio: 0.21
- p-value:
0.0001
- Significant: Yes
Study Design
- Study type: Candidate Region/Gene
- Technology: PCR-mediated site-directed mutagenesis
Reference:
17048073: Alpha1-antitrypsin heterozygosity plays a positive role in attainment of longevity.
Choice: Curate_Johnny
Created: June 30, 2013, midnight
Updated: Aug. 8, 2014, 1:05 p.m.
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