AAT M/Z/S

Polymorphism: AAT M/Z/S



Location: 14q32.1

Factor:
- Symbol: AAT
- Name: serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
- Entrez ID: 5265
- Ensembl ID: ENSG00000197249

Factors:
  • AAT serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 ( 5265 / ENSG00000197249 )

  • Age of cases: Minimum age 99
    Shorter lived allele: M, S

    Statistics
    - Number of cases/controls: 143 vs 255 (initial)
    - Odds ratio: 0.21
    - p-value: 0.0001
    - Significant: Yes

    Study Design
    - Study type: Candidate Region/Gene
    - Technology: PCR-mediated site-directed mutagenesis

    Reference:
    17048073: Alpha1-antitrypsin heterozygosity plays a positive role in attainment of longevity.

    Choice: Curate_Johnny
    Created: June 30, 2013, midnight
    Updated: Aug. 8, 2014, 1:05 p.m.

    Edit (Admin) | Delete

    Comment on This Data Unit