About
Objective
Purpose
Concepts
Philosophy
ILA
GCI
What Next?
Matrix
Terms
Privacy
Aspects
Facets
Research
Programming
Design
Professions
Scientist
Developer
Artist
Achievements
Ranks
Grades
Titles
Content
Data/Entries/Relations
Blog/Posts/Comments
Wiki/Pages/Tags
Articles (Reports/Reviews)
Ontology
Tutorials
Links
Media
Polls
Questionnaires
Repository
Annotations
Classifications
Tissues
Species
Interactions
Expressions
Profiles
Signatures
Intersections
Sets
Meta
Datasets
Create
References
Archive
Changes
Lifespan
Studies
Experiments
Measurements
Comparisons
Interventions
Factors
Variants
Assays
Strains
Regimens
Manipulations
Epistases
Experts
Profiles
Collaborations
Com
Messaging
Announcements
Video
Donate
Log in
or
Sign up
Denigma
»
Lifespan
»
Variants
» Variant = rs9536314
o
|
Admin
Mouse Lifespan Experiments
(
Hide
)
rs9536314
Polymorphism:
rs9536314
rs9536314
(
SNPedia
|
23andMe
)
Location:
13q12
Factor:
- Symbol:
KL
- Name:
klotho
- Entrez ID:
9365
- Ensembl ID:
ENSG00000133116
Factors:
KL
klotho
(
9365
/
ENSG00000133116
)
Description:
Assesment of CVD risk and KL polymorphism.
Ethnicity:
Ashkenazi Jewish
Age of cases:
>95
Longer lived allele:
TG (genotype)
Finding:
Positive
Statistics
- Number of cases/controls:
216 vs 309 (initial)
- p-value:
0.007 [0.007]
- Significant:
Yes
Study Design
- Classifications:
Longevity-Associated
- Study type:
Candidate Region/Gene
- Technology:
PCR
Reference:
15677572: Association between a functional variant of the KLOTHO gene and high-density lipoprotein cholesterol, blood pressure, stroke, and longevity.
Choice:
Curate
Created:
July 2, 2013, 2:54 a.m.
Updated:
Aug. 8, 2014, 1:06 p.m.
Edit
(
Admin
) |
Delete
Comment
on This
Data Unit
Comment on This Data Unit