C allele of this promoter SNP (rs1776180) is significantly enriched in female centenarians (German). This finding is replicated in 455 female French centenarians and 109 controls.
Ethnicity:French,
German Age of cases: Mean age 101.3 Shorter lived allele: G Longer lived allele: C Finding: Positive
Statistics - Number of cases/controls: 395 vs 411 (initial)
| 455 vs 109 (replication) - Odds ratio: 1.39 - p-value:
0.01
[<0.01]
- Significant: Yes
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