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Denigma
»
Lifespan
»
Variants
» Variant = rs10014396
o
|
Admin
Mouse Lifespan Experiments
(
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)
rs10014396
Polymorphism:
rs10014396
rs10014396
(
SNPedia
|
23andMe
)
Location:
4q21
Factor:
- Symbol:
SNCA
- Name:
synuclein, alpha (non A4 component of amyloid precursor)
- Entrez ID:
6622
- Ensembl ID:
ENSG00000145335
Factors:
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
(
6622
/
ENSG00000145335
)
Description:
rs10014396 and rs3775439 in strong LD=0.84. the population sample was subdivided into 7 age-classes
Ethnicity:
Caucasian
Age of cases:
>90 (oldest age group)
Shorter lived allele:
C
Statistics
- Number of cases/controls:
769 total (see notes) (initial)
- p-value:
0.021 [0.021]
- Significant:
Yes
Study Design
- Classifications:
Longevity-Associated
- Study type:
Candidate Region/Gene
- Technology:
genotyped on a Sequenom MassArray iPLEX platform
Reference:
22912757: Evaluation of the role of SNCA variants in survival without neurological disease.
Choice:
Curate
Created:
July 2, 2013, 2:48 a.m.
Updated:
Aug. 8, 2014, 1:06 p.m.
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