Measurements

ID experiment control background genotype manipulation diet temperature start mean median max num
186 Figure 5: Hac1-independent resistance to tunicamycin in afg3∆ and rpl20bΔ cells afg3;hac1 30.0 30.7 32.0 50.0 40
209 Figure 4 | Calorie restriction extends lifespan by regulating vacuolar acidity. S288c WT 31.0 31.5 50.0 32
164 Supplemental Figure 3: Growth curves and lifespan curves of respiratory dead or deficient strains idh2 30.0 30.7 31.0 60.0 595
175 Supplemental Figure 4: Unsuppressed growth of afg3∆, yta12∆, and mrpl32∆ and corresponding lifespan curves afg3 30.0 30.7 31.0 43.0
136 Figure 6: Deletion of AFG3 reduces cytoplasmic translation and extends life span by a Sir2-independent, Gcn4-dependent mechanism sir2;fob1;afg3 30.0 29.1 30.0 45.0 40
156 Supplemental Figure 2: Replicative lifespan curves of control strains sensitive to the tested stresses msn2;msn4 30.0 29.3 30.0 57.0 623
193 Figure 3 | Reduced vacuolar acidity causes mitochondrial dysfunction by disrupting amino acid homeostasis. S288c WT 28.95 29.0 51.0 32
213 Figure 4 | Calorie restriction extends lifespan by regulating vacuolar acidity. S288c WT 29.0 29.0 50.0 38
153 Supplemental Figure 2: Replicative lifespan curves of control strains sensitive to the tested stresses wild-type 30.0 28.3 29.0 46.0 55
158 Supplemental Figure 2: Replicative lifespan curves of control strains sensitive to the tested stresses hac1 30.0 29.1 29.0 57.0 543
196 Figure 2 | Vacuolar acidity is reduced in ageing cells and regulates mitochondrial function and lifespan. S288c WT 28.0 28.0 50.0 50
221 Figure 3. Increased life span of cardiotrophin 1 (CT-1)–null mice. C57BL6 WT 28.0 18
170 Supplemental Figure 4: Unsuppressed growth of afg3∆, yta12∆, and mrpl32∆ and corresponding lifespan curves mrpl23 30.0 28.2 28.0 51.0
184 Figure 5: Hac1-independent resistance to tunicamycin in afg3∆ and rpl20bΔ cells afg3 30.0 28.4 28.0 56.0 160
154 Supplemental Figure 2: Replicative lifespan curves of control strains sensitive to the tested stresses cta1 30.0 29.0 27.0 54.0 45
166 Supplemental Figure 3: Growth curves and lifespan curves of respiratory dead or deficient strains atp5 30.0 27.3 27.0 53.0 55
524 Fig. 3. Animal survival and growth Wistar Mutation 41.0 26.0 58.0 6
157 Supplemental Figure 2: Replicative lifespan curves of control strains sensitive to the tested stresses wild-type 30.0 26.5 26.0 56.0 545
155 Supplemental Figure 2: Replicative lifespan curves of control strains sensitive to the tested stresses wild-type 30.0 26.2 26.0 42.0 600
185 Figure 5: Hac1-independent resistance to tunicamycin in afg3∆ and rpl20bΔ cells hac1 30.0 25.6 26.0 40.0 20
161 Supplemental Figure 3: Growth curves and lifespan curves of respiratory dead or deficient strains wild-type 30.0 26.3 26.0 59.0 425
174 Supplemental Figure 4: Unsuppressed growth of afg3∆, yta12∆, and mrpl32∆ and corresponding lifespan curves rho0 30.0 26.1 26.0 50.0
217 Supplementary Figure 3. Phenotypes of VPH2 overexpression mimic those observed with VMA1 overexpression. S288c WT 26.0 26.0 50.0 53
173 Supplemental Figure 4: Unsuppressed growth of afg3∆, yta12∆, and mrpl32∆ and corresponding lifespan curves wild-type 30.0 26.7 26.0 57.0
163 Supplemental Figure 3: Growth curves and lifespan curves of respiratory dead or deficient strains wild-type 30.0 26.6 26.0 52.0 764