Denigma

Measurements

ID experiment control background genotype manipulation diet temperature start mean median max num
214 Figure 4 | Calorie restriction extends lifespan by regulating vacuolar acidity. ✘ S288c WT Dietary Restriction — — — 44.0 43.5 76.0 40
215 Figure 4 | Calorie restriction extends lifespan by regulating vacuolar acidity. ✘ S288c VMA1(OE) — — — — 42.0 43.0 75.0 36
210 Figure 4 | Calorie restriction extends lifespan by regulating vacuolar acidity. ✘ S288c WT Dietary Restriction — — — 45.0 45.0 75.0 31
323 Figure 1. Regulation of Lifespan by Modulating Genes in the TOR Signaling Pathway ✘ w1118 +/UAS-dTsc2 — — — — 56.0 — 74.0 126
85 Figure 2: Overexpression of CG6783 or CG13890 throughout the whole body extends lifespan, which is associated with diet restriction. ✘ white1118 da>EPCG6783 — — — — 46.0 58.0 72.0 —
326 Figure 1. Regulation of Lifespan by Modulating Genes in the TOR Signaling Pathway ✘ w1118 +UAS-dTORFRB — — — — 55.0 — 71.0 128
84 Figure 2: Overexpression of CG6783 or CG13890 throughout the whole body extends lifespan, which is associated with diet restriction. ✘ white1118 EPCG6783/+ — — — — 46.0 — 70.0 —
50 TABLE 2 Adult life span profiles A. At 25° ✔ — Canton-S — — 25.0 — 46.85 — 68.0 264
218 Supplementary Figure 3. Phenotypes of VPH2 overexpression mimic those observed with VMA1 overexpression. ✘ S288c VPH2(OE) — — — — 32.0 32.5 67.0 52
140 Figure 6: Deletion of AFG3 reduces cytoplasmic translation and extends life span by a Sir2-independent, Gcn4-dependent mechanism ✘ — sir2;fob1;afg3 Dietary Restriction — 30.0 — 45.3 48.0 67.0 20
63 TABLE 2 Adult life span profiles A. At 25° ✘ — atg8aep362 — — 25.0 — 41.9 — 66.0 150
525 Fig. 3. Animal survival and growth ✘ Wistar — Mutation — — — 62.0 42.0 66.0 6
88 Figure 2: Overexpression of CG6783 or CG13890 throughout the whole body extends lifespan, which is associated with diet restriction. ✔ white1118 Act-GS-Gal4>UAS-CG6783 — RU- — — 31.0 — 65.0 —
83 Figure 2: Overexpression of CG6783 or CG13890 throughout the whole body extends lifespan, which is associated with diet restriction. ✔ white1118 da/+ — — — — 26.0 32.0 64.0 —
139 Figure 6: Deletion of AFG3 reduces cytoplasmic translation and extends life span by a Sir2-independent, Gcn4-dependent mechanism ✘ — sir2;fob1 Dietary Restriction — 30.0 — 42.9 50.0 64.0 20
216 Figure 4 | Calorie restriction extends lifespan by regulating vacuolar acidity. ✘ S288c VMA1(OE) Dietary Restriction — — — 40.0 40.0 64.0 38
194 Figure 3 | Reduced vacuolar acidity causes mitochondrial dysfunction by disrupting amino acid homeostasis. ✘ S288c AVT1(OE) — — — — 37.0 37.0 62.0 32
60 TABLE 2 Adult life span profiles A. At 25° ✘ — light — — 25.0 — 24.92 — 61.0 247
164 Supplemental Figure 3: Growth curves and lifespan curves of respiratory dead or deficient strains ✘ — idh2 — — 30.0 — 30.7 31.0 60.0 595
169 Supplemental Figure 4: Unsuppressed growth of afg3∆, yta12∆, and mrpl32∆ and corresponding lifespan curves ✔ — wild-type — — 30.0 — 23.7 23.0 60.0 —
134 Figure 6: Deletion of AFG3 reduces cytoplasmic translation and extends life span by a Sir2-independent, Gcn4-dependent mechanism ✘ — afg3 — — 30.0 — 25.5 24.0 60.0 180
162 Supplemental Figure 3: Growth curves and lifespan curves of respiratory dead or deficient strains ✘ — idh1 — — 30.0 — 32.6 33.0 60.0 304
132 Figure 6: Deletion of AFG3 reduces cytoplasmic translation and extends life span by a Sir2-independent, Gcn4-dependent mechanism ✘ — afg3;fob1 — — 30.0 — 38.3 40.0 60.0 40
87 Figure 2: Overexpression of CG6783 or CG13890 throughout the whole body extends lifespan, which is associated with diet restriction. ✘ white1118 da>EPCG13890 — — — — 35.0 42.0 60.0 —
147 Figure 6: Deletion of AFG3 reduces cytoplasmic translation and extends life span by a Sir2-independent, Gcn4-dependent mechanism ✘ — rpl20b — — 30.0 — 33.8 36.0 60.0 59