561 | Figure 3 Increased BubR1 expression protects against spontaneous tumours and extends lifespan | ✔ | — | WT | — | — | — | — | — | — | 1250.0 | 60 |
553 | Figure S3 Overall and tumor-free survival of T23 animals is extended in males | ✘ | — | T23 | — | — | — | — | — | — | 1246.0 | 29 |
555 | Figure S3 Overall and tumor-free survival of T23 animals is extended in males | ✘ | — | T23 | — | — | — | — | — | — | 1246.0 | 29 |
565 | Figure 3 Increased BubR1 expression protects against spontaneous tumours and extends lifespan | ✘ | — | T23 | — | — | — | — | — | — | 1058.0 | 57 |
563 | Figure 3 Increased BubR1 expression protects against spontaneous tumours and extends lifespan | ✘ | — | T23 | — | — | — | — | — | — | 1058.0 | 57 |
556 | Figure S3 Overall and tumor-free survival of T23 animals is extended in females | ✔ | — | WT | — | — | — | — | — | — | 1057.0 | 30 |
560 | Figure S3 Overall and tumor-free survival of T23 animals is extended in females | ✘ | — | T23 | — | — | — | — | — | — | 1003.0 | 28 |
558 | Figure S3 Overall and tumor-free survival of T23 animals is extended in females | ✘ | — | T23 | — | — | — | — | — | — | 1003.0 | 28 |
551 | Figure S3 Overall and tumor-free survival of T23 animals is extended in males | ✔ | — | WT | — | — | — | — | — | — | 999.0 | 30 |
531 | Table 3 Parameters of life span in female SHR mice treated and not treated with metformin | ✘ | — | — | Mutation | — | — | — | 535.0 | 570.0 | 898.0 | 50 |
554 | Figure S3 Overall and tumor-free survival of T23 animals is extended in males | ✔ | — | T-GFP | — | — | — | — | — | — | 882.0 | 22 |
562 | Figure 3 Increased BubR1 expression protects against spontaneous tumours and extends lifespan | ✘ | — | T-GFP | — | — | — | — | — | — | 882.0 | 36 |
564 | Figure 3 Increased BubR1 expression protects against spontaneous tumours and extends lifespan | ✔ | — | T-GFP | — | — | — | — | — | — | 882.0 | 36 |
552 | Figure S3 Overall and tumor-free survival of T23 animals is extended in males | ✘ | — | T-GFP | — | — | — | — | — | — | 882.0 | 22 |
530 | Table 3 Parameters of life span in female SHR mice treated and not treated with metformin | ✔ | — | — | Mutation | — | — | — | 388.0 | 297.0 | 814.0 | 50 |
559 | Figure S3 Overall and tumor-free survival of T23 animals is extended in females | ✔ | — | T-GFP | — | — | — | — | — | — | 803.0 | 14 |
557 | Figure S3 Overall and tumor-free survival of T23 animals is extended in females | ✘ | — | T-GFP | — | — | — | — | — | — | 803.0 | 14 |
529 | Table 4 Effect of metformin on parameters of life span in female HER-2/neu mice | ✘ | — | — | Mutation | — | — | — | 285.0 | — | 340.0 | 32 |
528 | Table 4 Effect of metformin on parameters of life span in female HER-2/neu mice | ✔ | — | — | Mutation | — | — | — | 264.0 | — | 311.0 | 34 |
327 | Figure 1. Regulation of Lifespan by Modulating Genes in the TOR Signaling Pathway | ✘ | w1118 | da-GAL4/UAS-dTORFRB | — | — | — | — | 72.0 | — | 89.0 | 112 |
324 | Figure 1. Regulation of Lifespan by Modulating Genes in the TOR Signaling Pathway | ✘ | w1118 | da-GAL4/UAS-dTsc2 | — | — | — | — | 69.0 | — | 88.0 | 134 |
197 | Figure 2 | Vacuolar acidity is reduced in ageing cells and regulates mitochondrial function and lifespan. | ✘ | S288c | VMA1(OE) | — | — | — | — | 39.0 | 39.0 | 80.0 | 56 |
325 | Figure 1. Regulation of Lifespan by Modulating Genes in the TOR Signaling Pathway | ✔ | w1118 | +/da-GAL4 | — | — | — | — | 48.0 | — | 79.0 | 133 |
138 | Figure 6: Deletion of AFG3 reduces cytoplasmic translation and extends life span by a Sir2-independent, Gcn4-dependent mechanism | ✘ | — | sir2;fob1;afg3 | — | — | 30.0 | — | 46.0 | 44.0 | 78.0 | 20 |
322 | Figure 1. Regulation of Lifespan by Modulating Genes in the TOR Signaling Pathway | ✔ | w1118 | +/da-GAL4 | — | — | — | — | 58.0 | — | 78.0 | 133 |