his-5 RNAi | Knockdown of his-5 via RNAi started after the animal reached the late L4 stage increase or decreases lifespan by 2 and 3%, respectively [22103665]. | — | — | — | — |
kat-1 RNAi | Knockdown of kat-1 via RNAi started after the animal reached the late L4 stage has no significant effect on mean lifespan [22103665]. | — | — | — | — |
CG11015 RNAi | Under rich nutritional conditions lifespan of CG11015 RNAi treated animals is indistinguishable from that of controls, while upon DR, lifespan extension is diminished in males and females [19804760]. | — | — | — | — |
C33H5.18 RNAi | RNA interference of C33H5.18 decreases median lifespan by 44% in wild type animals, 77% in a daf-2 background and 14% in daf-2/daf-16 double mutants [18006689]. | — | — | -44 | — |
YHB1 deletion | Deleting YHB1 partially abolished DR-induced replicative lifespan extension, whereas deleting SFA1 alone had no effect. sfa1;yhb1 double mutant cancels out the ability of moderate DR to extend replicative lifespan, but not chronological lifespan. Yhb1 and Sfa1 may play redundant roles [21584246]. | Yeast | — | — | — |
grs-1 RNAi | grs-1 RNAi in the adulthood extends the lifespan [New longevity regulators]. | Worm | — | — | — |
F38E11.5 RNAi | F38E11.5 RNAi in the adulthood extends the lifespan [New longevity regulators]. | Worm | — | — | — |
F54D5.11 RNAi | F54D5.11 RNAi in the adulthood extends the lifespan [New longevity regulators]. | Worm | — | — | — |
rpn-7 RNAi | rpn-7 RNAi in the adulthood extends the lifespan [New longevity regulators]. | Worm | — | — | — |
par-6 RNAi | par-6 RNAi in the adulthood extends the lifespan [New longevity regulators]. | Worm | — | — | — |
lys-1 RNAi | lys-1 RNAi in the adulthood extends the lifespan [New longevity regulators]. | Worm | — | — | — |
ndc-80 RNAi | ndc-80 RNAi in the adulthood extends the lifespan [New longevity regulators]. | Worm | — | — | — |
let-92 RNAi | let-92 RNAi in the adulthood extends the lifespan [New longevity regulators]. | Worm | — | — | — |
his-2 RNAi | his-2 RNAi in the adulthood extends the lifespan [New longevity regulators]. | Worm | — | — | — |
gsk-3 RNAi | gsk-3 RNAi in the adulthood extends the lifespan [New longevity regulators]. | Worm | — | — | — |
F16D3.4 RNAi | F16D3.4 RNAi in the adulthood extends the lifespan [New longevity regulators]. | Worm | — | — | — |
eif-3.E RNAi | eif-3.E RNAi in the adulthood extends the lifespan [New longevity regulators]. | Worm | — | — | — |
rsp-8 RNAi | rsp-8 RNAi in the adulthood extends the lifespan [New longevity regulators]. | Worm | — | — | — |
B0393.6 RNAi | B0393.6 RNAi in the adulthood extends the lifespan [New longevity regulators]. | Worm | — | — | — |
T04A8.11 RNAi | T04A8.11 RNAi in the adulthood extends the lifespan [New longevity regulators]. | Worm | — | — | — |
aph-2 RNAi | aph-2 RNAi in the adulthood extends the lifespan [New longevity regulators]. | Worm | — | — | — |
cdk-1 RNAi | cdk-1 RNAi in the adulthood extends the lifespan [New longevity regulators]. | Worm | — | — | — |
dpy-22 RNAi | dpy-22 RNAi in the adulthood extends the lifespan [New longevity regulators]. | Worm | — | — | — |
evl-20 RNAi | evl-20 RNAi in the adulthood extends the lifespan [New longevity regulators]. | Worm | — | — | — |
pat-2 RNAi | pat-2 RNAi in the adulthood extends the lifespan [New longevity regulators]. | Worm | — | — | — |