Denigma

Interventions

  • Species: + -
    House mouse « 
  • Manipulation: + -
    Gain‑of‑Function «  Overexpression «  Mutation (1)   Deletion (1)   Gene Therapy (1)  
    • name effect species mean median maximum
    TXN overexpression Overexpression of TXN1 in transgenic C57BL/6 mice resulted in extended median (35%) and maximum (22%) lifespan. Telomerase activity in spleen tissues of TXN1 overexpressing mice is higher than tha in wild-type [12230882]. Mouse — +35 +22
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    • 1 of 26 interventions
    Interventions are an extension of GenAge and GenDR.