Denigma

Interventions

  • Species: + -
    Fruit fly (2)  
  • Manipulation: + -
    Transposition «  Knockout «  Loss‑of‑Function (2)   Mutation (1)  
    • name effect species mean median maximum
    Hsp22 transposition Animals that do not express Hsp22 (due to a transposition into its transcriptional starting site) have a 40% decrease in lifespan, exhibit a 30% decrease in locomotor activity and are sensitive to mild stress [20036725]. Fly -40 — —
    sgg transposition Several insertions of P-based vectors in the structural part of sgg are associated with alterations of male and female lifespan [22661237]. Fly — — —
    • 2 interventions
    Interventions are an extension of GenAge and GenDR.