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Ontology of Gerontology
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Interventions
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Species:
+
-
Budding yeast (1)
Manipulation:
+
-
Deletion «
Gain‑of‑Function «
Mutation «
Knockout «
name
effect
species
mean
median
maximum
RPL31A deletion
Deletion of RPL31A increases mean replicative lifespan by 45% [
16293764
]. Mean replicative lifespan increases by 35% in the alpha strain and 50% in a strain [
19030232
;
18423200
]. Mean replicative lifespan of the RPL31A deletion mutant increases by 35% in the ORF collection and by 29% in the remade strain [
22377630
]. RPL31A deletion increases significantly replicative lifespan [
17174052
]. Deletion of RPL31A extends replicative lifespan and is not further extended by 0.05% glucose restriction [
18423200
].
Yeast
+29 to +50
—
—
1 intervention
Interventions are an extension of
GenAge
and
GenDR
.