tax-4 mutation

Species: Nematode (Taxid: 6239)
Factor: tax-4
Manipulation: Loss-of-Function, Knockout, Mutation
Effect:

Recessive loss-of-function allele in tax-4 can increase lifespan by up to 100%. Lifespan extension by tax-4 mutation is suppressed by daf-16 and gonad ablation [10617200].

tax-4 mutants are thermotaxis and chemotaxis defective [8893027; 8348618]. Mutants are slighlty dauer constitutive and form dauers at 27 degree Celsius [9486798].

Mean: +100

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR



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