Denigma

RAS1 deletion

Species: Budding yeast (Taxid: 4932)
Factor: RAS1
Manipulation: Loss-of-Function, Knockout, Mutation, Deletion
Effect:

Deletion in RAS1 increases mean (23%) and maximum (29%) replicative lifespan (in SP1) [8034612]. RAS1 deletion increases replicative lifespan by 15% in the alpha strain [19030232]. However, deletion of RAS1 slightly shortens chronological lifespan (in SP1) [12586694].

Mean: +15 to +23
Maximum: +29

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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