Denigma

Homozygous Prdx1 knockout

Species: House mouse (Taxid: 10090)
Factor: Prdx1
Manipulation: Loss-of-Function, Knockout, Mutation, Deletion
Effect:

Homozygous Prdx1 knockout mice have a lifespan significant shorter than +/+ and +/- littermates and develop severe haemolytic anaemia and several malignant cancers (starting at about 9 months of age) [12891360]


Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

    • Edit / Update (Admin) | Delete

    Comment on This Data Unit