Pcmt overexpression

Species: House mouse (Taxid: 10090)
Factor: Pcmt
Manipulation: Gain-of-Function, Overexpression
Effect:

Overexpression of Pcmt extends lifespan by 32-39% at 29 degrees but not at 25 degrees [11742076].

The adult lifespan of animals overexpressing Pcmt is extended [18772467].

Mean: 0 to 39

References:
  • 11742076: Extension of the Drosophila lifespan by overexpression of a protein repair methyltransferase.
  • 18772467: Protein-repair and hormone-signaling pathways specify dauer and adult longevity and dauer development in Caenorhabditis elegans.


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR



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