Denigma

ovo mutation

Species: Fruit fly (Taxid: 7227)
Factor: ovo
Manipulation: Loss-of-Function, Mutation
Effect:

The dominant ovoD1 allele extends female lifespan by approximately 50%. It does not synergize or prevent life-extension caused by chico [10617470; 11292874].

ovoD1 mutants are sterile [Mevel-Ninio et al. 1991].

Mean: +50

References:
  • 11292874: Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein.
  • 10617470: A delayed wave of death from reproduction in Drosophila.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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