NNT1 deletion

Species: Budding yeast (Taxid: 4932)
Factor: NNT1
Manipulation: Loss-of-Function, Knockout, Mutation, Deletion
Effect:

Deletion of NNT1 decreases mean and maximum lifespan by 9 and 19%. 0.5% glucose DR extends the mean and maximum lifespan of NNT1 deletion mutants by 35 and 40%. NNT1 deletion decreases rDNA silencing [12736687].

Mean: -9
Maximum: -19

References:
  • 12736687: Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae.


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR



  • Edit / Update (Admin) | Delete

    Comment on This Data Unit