Denigma

LAG2 overexpression

Species: Budding yeast (Taxid: 4932)
Factor: LAG2
Manipulation: Gain-of-Function, Overexpression
Effect:

When LAG2 is overexpressed in SP1 strain, the mean and maximum replicative lifespan is extended by about 36% and 54%, respectively. Overexpression induced at generation 12 similarly increases replicative lifespan [8760941].

Mean: +36
Maximum: +54

References:
  • 8760941: LAG2, a gene that determines yeast longevity.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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