Denigma

hsp-6 overexpression

Species: Nematode (Taxid: 6239)
Factor: hsp-6
Manipulation: Gain-of-Function, Overexpression
Effect:

Overexpression of hsp-6 from a muscle-specific promoter extends lifespan mean and maximum lifespan by 43 and 45% relatively to animals expressing GFP from the same promoter [11959102].

Mean: +43
Maximum: +45

References:
  • 11959102: Extended longevity of Caenorhabditis elegans by knocking in extra copies of hsp70F, a homolog of mot-2 (mortalin)/mthsp70/Grp75.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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