HOG1 deletion

Species: Budding yeast (Taxid: 4932)
Factor: HOG1
Manipulation: Loss-of-Function, Knockout, Mutation, Deletion
Effect:

Deletion of HOG1 shortens replicative lifespan by 25% and prevents lifespan extension by high osmolarity [12391171]. HOG1 deletion slightly decreases chronological lifespan and partially suppresses the premature aging phenotype and short lifespan of ISC1 deletion [22445853].

Mean: -25

References:
  • 12391171: High osmolarity extends life span in Saccharomyces cerevisiae by a mechanism related to calorie restriction.


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR



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