Hk mutation

Species: Fruit fly (Taxid: 7227)
Factor: Hk
Manipulation: Loss-of-Function, Mutation
Effect:

Genetic mutation in Hyperkinetic shortens lifespan through acceleration of the aging process. At 25 degree Celsius mean and maximum lifespan is reduced by 29 and 32%, while by 18 degree Celsius the reduction is 59 and 39% [8582611].

Mean: -29 to -59
Maximum: -32 to -39

References:
  • 8582611: Regulation of gene expression is linked to life span in adult Drosophila.


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR



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