Denigma

daz-1 mutation

Species: Nematode (Taxid: 6239)
Factor: daz-1
Manipulation: Loss-of-Function, Mutation
Effect:

Mutation of daz-1 has no effect on lifespan [11799246]. daz-1 mutants are sterile and have a gonad that contains small nuclei and no oocytes [10662646]. Although sperm production is normal, oocytes precursors arrest at meiotic prophase and undergo apoptosis


References:
  • 11799246: Regulation of life-span by germ-line stem cells in Caenorhabditis elegans.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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