daf-6 mutation

Species: Nematode (Taxid: 6239)
Factor: daf-6
Manipulation: Loss-of-Function, Mutation
Effect:

Loss-of-function mutations in daf-6 extend lifespan by up to 50% [10617200]. daf-6 mutants are dauer defective, chemotaxis defective, osmotic aviodance (osm), male mate poorly, and, dye filling defective [2428682]. Mutants of daf-6 have defective sheath cells causing the amphid and phasmids pores to be closed.

Mean: +50

References:
  • 10617200: Regulation of lifespan by sensory perception in Caenorhabditis elegans.
  • 2428682: Mutant sensory cilia in the nematode Caenorhabditis elegans.


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR



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