Denigma

daf-19 mutation

Species: Nematode (Taxid: 6239)
Factor: daf-19
Manipulation: Loss-of-Function, Knockout, Mutation, Deletion
Effect:

Loss-of-function mutations in daf-19 increase lifespan up to 50% [10617200]. daf-19 mutants are dauer constitutive, dye-filling defective, and lack sensory cilia [7219552; 9475731].

Mean: +50

References:
  • 10617200: Regulation of lifespan by sensory perception in Caenorhabditis elegans.
  • 7219552: Interacting genes in nematode dauer larva formation.
  • 9475731: Analysis of osm-6, a gene that affects sensory cilium structure and sensory neuron function in Caenorhabditis elegans.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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