Denigma

hsb-1 mutation

Species: Nematode (Taxid: 6239)
Factor: hsb-1
Manipulation: Loss-of-Function, Knockout, Mutation
Effect:

hsb-1(cg116) mutation at 20 degree Celsius extends mean, 75%ile, and maximum lifespan by 57-60%, 52-59%, and 37-69%.

Mean: +57 to +60
Maximum: +37 to +69

References:
  • 22265419: HSF-1 regulators DDL-1/2 link insulin-like signaling to heat-shock responses and modulation of longevity.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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