Denigma

Rapamycin treatment

Species: Fruit fly (Taxid: 7227)
Factor: Rapa
Manipulation: Diet Intervention, Drug treatment
Effect:

Treatment of Drosophila imago with rapamycin induces increases of median (by 5-6%) lifespan (p < 0.01) in males and females, respectively and increase of maximum lifespan (by 33%) in females (p < 0.01) [22661237].

Low dose of LY294002 (5 microM) slightly increase the median and maximum lifespan [20017609].

Median: +5 to +6
Maximum: +33

References:
  • 22661237: The second international conference "genetics of aging and longevity".
  • 20017609: Pharmacological inhibition of phosphoinositide 3 and TOR kinases improves survival of Drosophila melanogaster.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

    • Edit / Update (Admin) | Delete

    Comment on This Data Unit