Denigma

mdt-15 mutation

Species: Nematode (Taxid: 6239)
Factor: mdt-15
Manipulation: Loss-of-Function, Knockout, Mutation, Deletion
Effect:

mdt-15(tm2182) mutation does not affect lifespan on ad libitum, but further increases the lifespan when combined with DR (starting at the 4th day of adulthood) even more as wild-type [22132200].


References:
  • 22132200: The MDT-15 subunit of mediator interacts with dietary restriction to modulate longevity and fluoranthene toxicity in Caenorhabditis elegans.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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