Denigma

L-proline supplementation

Species: Nematode (Taxid: 6239)
Factor: Pro
Manipulation: Diet Intervention, Drug treatment
Effect:

L-proline supplementation increases lifespan by 5.8 and 13.6% (mean and maximum lifespan) [22482728].

Mean: +6
Maximum: +14

References:
  • 22482728: Impaired insulin/IGF1 signaling extends life span by promoting mitochondrial L-proline catabolism to induce a transient ROS signal.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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