Denigma

INP53 deletion

Species: Budding yeast (Taxid: 4932)
Factor: INP53
Manipulation: Loss-of-Function, Knockout, Mutation, Deletion
Effect:

Deletion of INP53 increases mean replicative lifespan by 31% [16293764]. INP53 deletion increases replicative lifespan by 31% in the alpha strain and by 10% in the a strain [18340043].

Mean: +31

References:
  • 18340043: Quantitative evidence for conserved longevity pathways between divergent eukaryotic species.
  • 16293764: Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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