272N18 Treatment

Species: Nematode (Taxid: 6239)
Factor:
Manipulation:
Effect:

272N18 (3-(3-nitrophenyl)-11-phenyl-2,3,4,5,10,11-hexohydro-1H-dibenzo[b,e] [1,4]diazepin-1-one dihdrochloride) increases lifespan by 20%, bears a structural resemblance to certain human antidepressants that affect signalling by the neurotransmitter serotonin.


References:
  • 19686215: A high-throughput screen for chemicals that increase the lifespan of Caenorhabditis elegans.




  • Edit / Update (Admin) | Delete

    Comment on This Data Unit