VPS8 deletion

Species: Budding yeast (Taxid: 4932)
Factor: VPS8
Manipulation: Loss-of-Function, Knockout, Mutation, Deletion
Effect:

Lack of VPS8 reduces lifespan under starvation conditions to a level similiar to that of wild-type cells incubated in synthetic complete medium and therefore blocked the lifespan-extending effect of DR [20657825].


References:
  • 20657825: Genome-wide screen in Saccharomyces cerevisiae identifies vacuolar protein sorting, autophagy, biosynthetic, and tRNA methylation genes involved in life span regulation.


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR



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